Estimate mean gene profiles — estimate.geneprofile • MultiRD

Mean gene profiles are estimated given estimated proportions

estimate.geneprofile(
bulk.data,
gene.used,
celltype.unique,
cluster.identifier,
prop.est
)

Arguments

bulk.data	ExpressionSet object for a given bulk data
gene.used	Pool of marker genes to be estimated
celltype.unique	A list of cell types. It should match the order in list.marker
cluster.identifier	Indentifiers to indicate which cell type a given marker gene belongs to. They are coded as 1,2,3,...,T to represent T cell types, respectively
prop.est	Estimated cell type proprotion matrix

Value

This function returns a matrix containing estimated mean gene profiles for all cell types, with rows indicating genes and columns indicating cell types.